Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial.
We conducted a randomized, double-blind, placebo-controlled clinical trial to explore how magnesium treatments influence kidney stones, specifically for those with high levels of oxalate in their urine. Our study involved 90 participants with a history of calcium kidney stones, all of whom were experiencing idiopathic hyperoxaluria. They were divided into three groups receiving either magnesium oxide (MgO), magnesium citrate (MgCit), or a placebo for eight weeks, while their diets were monitored to keep nutritional intake consistent.
After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.
Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.
Read More
8
Dietary magnesium may reduce stones
Dietary Magnesium Intake and Kidney Stone: The National Health and Nutrition Examination Survey 2011-2018.
We wanted to understand the relationship between dietary magnesium intake and the prevalence of kidney stones. By examining data from the National Health and Nutrition Examination Survey spanning 2011 to 2018, we were able to analyze the self-reported history of kidney stones among participants.
Our findings indicated that those who consumed higher amounts of magnesium appeared to have a lower likelihood of experiencing kidney stones. Specifically, the average daily magnesium intake was lower in individuals with kidney stones, suggesting that magnesium might play a role in kidney stone formation.
In our analysis, we discovered that when grouped into different levels of magnesium intake, those in the highest intake category had significantly reduced odds of developing kidney stones compared to those in the lowest intake category. This trend suggests a protective effect of dietary magnesium against kidney stone disease.
While our results are promising, we recognize that further research is needed to determine if there is a direct causal relationship between magnesium intake and kidney stones. The evidence points towards a beneficial link, but more prospective studies will help clarify this important topic for better health outcomes.
Read More
3
Magnesium affects urine, not stones
Magnesium Decreases Urine Supersaturation but Not Calcium Oxalate Stone Formation in Genetic Hypercalciuric Stone-Forming Rats.
We explored the effects of magnesium on kidney stones, focusing specifically on how it might influence urinary chemistry and calcium oxalate (CaOx) stone formation. Using genetic hypercalciuric stone-forming rats, we divided the animals into three groups, each receiving different levels of magnesium for six weeks.
After analyzing the 24-hour urine collection, we observed notable changes depending on magnesium intake. Those on a low magnesium diet had higher urinary supersaturation levels of CaOx, while the high magnesium group showed a significant decrease in urinary supersaturation. However, we need to stress that despite these changes in urine chemistry, magnesium did not impact the actual formation of calcium oxalate stones within the study period.
In summary, while increasing dietary magnesium can lower supersaturation in urine, it doesn't appear to prevent the formation of calcium oxalate stones in this rat model. This finding is important for understanding the role of magnesium in kidney stone prevention.
Read More
Most Useful Reviews
7.5
Effective for kidney stones
1 people found this helpful
For urolithiasis, magnesium citrate was prescribed by my urologist to dissolve oxalates in my kidneys. I took 200 mg once a day, and because it helps with stools, it’s a suitable option. If my review helped you, please let me know.
Read More
9
High bioavailability confirmed
Magnesium citrate is an affordable and highly bioavailable form of magnesium. Clinical studies confirm that it reduces the formation of kidney stones and helps to alkalinise urine.
Read More
7.5
Best magnesium form
1 people found this helpful
I’ve long sought out magnesium for my husband, who has kidney stones. This form is the best for him, and everyone knows Solgar for its excellent quality!
Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial.
We conducted a randomized, double-blind, placebo-controlled clinical trial to explore how magnesium treatments influence kidney stones, specifically for those with high levels of oxalate in their urine. Our study involved 90 participants with a history of calcium kidney stones, all of whom were experiencing idiopathic hyperoxaluria. They were divided into three groups receiving either magnesium oxide (MgO), magnesium citrate (MgCit), or a placebo for eight weeks, while their diets were monitored to keep nutritional intake consistent.
After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.
Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.
Read More
8
Magnesium's complex role in kidney stones
Machine Learning Models Decoding the Association Between Urinary Stone Diseases and Metabolic Urinary Profiles.
We analyzed how magnesium levels in urine might influence the occurrence of kidney stones. The study involved a mix of 468 patients who had been diagnosed with various types of urinary stones and underwent a detailed 24-hour urine analysis.
Our investigation found that 24-hour urinary magnesium was positively associated with both kidney stones and stones in multiple locations. Specifically, higher levels of magnesium corresponded with increased risk for these conditions. This relationship was particularly interesting because magnesium was highly correlated with another mineral, urinary phosphorus.
On the flip side, we also identified that 24-hour urinary creatinine acted as a protective factor against kidney and ureter stones, suggesting that maintaining adequate creatinine levels could potentially help prevent these types of stones. Additionally, eGFR (estimated Glomerular Filtration Rate) was noted as a risk factor especially for ureter stones and those that appear in multiple locations.
Ultimately, our study underscores that while magnesium is linked to stone formation, there are other contributing factors at play as well. This knowledge could guide improvements in dietary or medicinal strategies aimed at preventing kidney stones, especially emphasizing the need for a balanced intake of minerals in our diets.
Read More
8
Magnesium's role in kidney stones
Oral supplementation with probiotics, potassium citrate, and magnesium in reducing crystalluria in stone formers: A phase II study.
We analyzed a study focused on the effects of a combination of probiotics, potassium, and magnesium on kidney stone formation, specifically looking at crystalluria, which is the presence of crystals in urine that can signal the recurrence of kidney stones. The study involved 23 patients with calcium oxalate kidney stones who had crystalluria but normal metabolic profiles.
Over the course of 20 days, the patients received daily supplementation with beneficial bacteria, including Lactobacillus paracasei, Lactobacillus plantarum, and Bifidobacterium breve, along with potassium citrate and magnesium. After treatment, we observed a decrease in the presence of crystalluria at multiple follow-up points—1, 3, 6, and 12 months later.
Interestingly, while we noted that the probiotics and other agents helped reduce crystalluria, the study did not isolate the specific effects of magnesium alone. Therefore, we must be cautious in drawing firm conclusions about magnesium’s standalone effectiveness in this context.
Overall, the findings suggest that combining these supplements can be beneficial for patients with kidney stones, but the role of magnesium specifically requires further investigation.
Read More
8
Magnesium improves urine levels
Magnesium Supplementation Increases Urine Magnesium and Citrate in Stone Formers With Hypomagnesuria.
We aimed to find out how magnesium affects urinary levels of magnesium and citrate in people who form kidney stones and have low magnesium in their urine. By examining medical records, we compared two approaches: one group increased their magnesium through foods, while the other group received magnesium supplements.
We focused on adult patients whose urine magnesium levels were less than 70 mg a day. Following our recommendations, we observed significant changes after both dietary increases and supplementation. Those who took magnesium supplements showed a more pronounced improvement—about 88% were able to raise their urine magnesium to at least 70 mg a day, compared to just 58% in the dietary group.
Interestingly, only the supplement group showed a noticeable increase in urine citrate levels, which is also crucial in the prevention of kidney stones. Overall, both dietary and supplemental magnesium effectively improved magnesium levels, but supplementation had greater success in achieving desirable levels.
Read More
8
Dietary magnesium may reduce stones
Dietary Magnesium Intake and Kidney Stone: The National Health and Nutrition Examination Survey 2011-2018.
We wanted to understand the relationship between dietary magnesium intake and the prevalence of kidney stones. By examining data from the National Health and Nutrition Examination Survey spanning 2011 to 2018, we were able to analyze the self-reported history of kidney stones among participants.
Our findings indicated that those who consumed higher amounts of magnesium appeared to have a lower likelihood of experiencing kidney stones. Specifically, the average daily magnesium intake was lower in individuals with kidney stones, suggesting that magnesium might play a role in kidney stone formation.
In our analysis, we discovered that when grouped into different levels of magnesium intake, those in the highest intake category had significantly reduced odds of developing kidney stones compared to those in the lowest intake category. This trend suggests a protective effect of dietary magnesium against kidney stone disease.
While our results are promising, we recognize that further research is needed to determine if there is a direct causal relationship between magnesium intake and kidney stones. The evidence points towards a beneficial link, but more prospective studies will help clarify this important topic for better health outcomes.
For urolithiasis, magnesium citrate was prescribed by my urologist to dissolve oxalates in my kidneys. I took 200 mg once a day, and because it helps with stools, it’s a suitable option. If my review helped you, please let me know.
Read More
9
High bioavailability confirmed
Magnesium citrate is an affordable and highly bioavailable form of magnesium. Clinical studies confirm that it reduces the formation of kidney stones and helps to alkalinise urine.
Read More
7.5
Best magnesium form
1 people found this helpful
I’ve long sought out magnesium for my husband, who has kidney stones. This form is the best for him, and everyone knows Solgar for its excellent quality!
Read More
6
Removes stones effectively
1 people found this helpful
Magnesium citrate is suitable for those with kidney stones and helps to gradually eliminate them from the body. It also benefits those suffering from persistent constipation.
Read More
6
Questionable quality
1 people found this helpful
I regularly consume magnesium because it prevents kidney stones. This particular magnesium gave me strong laxative effects, yet I questioned its quality. I find magnesium citrate crucial for kidney stones, but my husband did not notice any changes. It's worth trying to see if it works for you.
Kidney stones are hard deposits made of minerals and salts that form inside your kidneys. While they can vary in size from tiny particles to large stones, they all begin as crystallized substances that develop when urine contains more crystal-forming substances than the fluid in your urine can dilute. When the crystals stick together, they can form stones, which may cause severe pain, especially when they pass through the urinary tract. Common types of kidney stones include calcium stones, struvite stones, uric acid stones, and cystine stones.
The symptoms of kidney stones can include sharp pain in the side and back, pain during urination, pink or red urine, and frequent urination. Various factors can increase the risk of developing kidney stones, including dehydration, certain dietary choices, and genetic predisposition. Preventing kidney stones often involves drinking plenty of water, avoiding excessive salt and animal protein, and ensuring a balanced intake of calcium. For those who suffer from kidney stones, a medical evaluation may be necessary to determine the best management and preventive strategies.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium may play a supportive role in the prevention of kidney stones, particularly calcium oxalate stones, which are the most common type. Research suggests that adequate magnesium intake can help inhibit the crystallization of calcium oxalate in the kidneys. Magnesium works by binding to oxalate, which can reduce the amount of oxalate available to form stones. This process could potentially decrease the likelihood of developing kidney stones in individuals who are prone to them.
However, it's important to note that while magnesium may help, it should not be viewed as a standalone solution for kidney stone prevention or treatment. A well-rounded approach that includes staying hydrated, managing dietary oxalate intake, maintaining appropriate calcium levels, and consulting healthcare professionals for personalized advice remains crucial. If you have a history of kidney stones or are concerned about your risk, it's best to discuss magnesium supplementation and dietary changes with your doctor to determine the most effective and safe strategy for your specific situation.
When it comes to taking magnesium citrate for kidney stones, user experiences vary significantly. Some users report that it helps to gradually eliminate stones from the body, whereas others mention not noticing any immediate changes. For example, one user highlighted that their husband did not see any results despite consuming magnesium citrate regularly Read Review. Another noted the supplement's laxative effects but also questioned its quality Read Review.
In general, it seems that most users suggest giving magnesium citrate time to show effects, as gradual changes might be expected. However, specific timelines for seeing noticeable results are not clearly defined in the reviews. The variability in user experiences suggests that while some may find relief or improvement within a few weeks, others may not notice any changes for a longer period. It is often recommended to consult with a healthcare provider to determine an appropriate timeline based on individual health conditions.
Scientific research on the relationship between magnesium supplementation and kidney stones presents a mixed yet intriguing picture. For instance, a study analyzing data from the National Health and Nutrition Examination Survey found that higher dietary magnesium intake was associated with a lower prevalence of kidney stones, suggesting a potential protective effect against their formation [8]. However, another study found that increased levels of urinary magnesium were correlated with a higher risk of kidney stones, indicating that excess magnesium may not be beneficial for everyone [2]. Additionally, while magnesium supplementation, especially in the form of magnesium citrate, showed promising results in reducing oxalate excretion, a crucial factor in stone formation, the complexities of its effects highlight the need for more tailored approaches depending on individual health conditions [5].
Furthermore, while magnesium appears to have some positive impacts, it is not a panacea. Research indicates that magnesium's benefits may plateau at a daily intake of around 350 mg and that other factors such as urinary citrate levels are critical in preventing kidney stones [3]. Overall, while magnesium supplementation can be a part of a broader strategy for kidney stone prevention, it should be approached with caution, emphasizing individual health needs and dietary balance to maximize effectiveness [6].
Based on user reviews, many individuals have reported positive improvements in symptoms related to kidney stones after using magnesium citrate. Users like those who took 200 mg daily noted that it helped in dissolving oxalates in their kidneys and in managing constipation, suggesting it could be a suitable option for those experiencing discomfort due to stones Read Review. Additionally, some users have highlighted clinical studies confirming that magnesium citrate can reduce kidney stone formation and alkalinize urine, thereby providing a dual benefit for individuals struggling with urolithiasis Read Review.
While many users praise magnesium citrate for its effectiveness, experiences can vary significantly. For instance, some individuals have not observed any improvements despite consistent use, which underscores the importance of individual health factors Read Review. However, there are plenty of testimonials affirming its helpfulness in gradually eliminating kidney stones and enhancing digestive health, with positive experiences being frequently reported among those who trust the quality of well-known brands like Solgar Read Review. As with any supplement, it's wise to approach magnesium citrate with realistic expectations and consult a healthcare provider to address specific health needs.
Based on user reviews, combining magnesium citrate with other supplements for handling kidney stones seems to yield mixed experiences. Several users have praised magnesium citrate for its effectiveness in dissolving oxalates and reducing the formation of kidney stones, with some users noting that it helps manage associated issues like constipation Read Review. However, the results can vary greatly; while some users experience positive outcomes, such as enhanced digestive health and decreased symptoms Read Review, others report no significant changes despite consistent use Read Review.
Additionally, there is a suggestion from users that quality matters when selecting magnesium citrate, with brands like Solgar receiving commendations for their reliability and effectiveness in addressing kidney stone issues Read Review. Overall, while magnesium citrate is generally regarded as a beneficial supplement for kidney stones, users recommend that individuals considering combining it with other supplements be aware of their unique health circumstances and consult a healthcare provider to ensure optimal results.
According to research, the optimal dose of magnesium for treating kidney stones hovers around the 350 mg mark per day, particularly for individuals aged 50 and older. A study analyzing data from the National Health and Nutrition Examination Survey found that higher magnesium intake was associated with a lower risk of developing kidney stones, revealing a significant protective effect, especially in women [3]. These findings suggest maintaining a balanced diet rich in magnesium can be beneficial for those at risk of kidney stones.
However, it's essential to note that while increasing dietary magnesium can help, there are limits to its efficacy; the protective benefits seem to plateau around 350 mg per day. Going beyond this amount might not yield additional advantages in reducing kidney stone risk [3]. Other factors like urinary excretion levels, in relation to minerals such as calcium and oxalate, can also play a crucial role in kidney stone formation, suggesting that a comprehensive approach to dietary management, potentially including supplementation, may be needed for optimal results.
6
Questionable quality
1 people found this helpful
I regularly consume magnesium because it prevents kidney stones. This particular magnesium gave me strong laxative effects, yet I questioned its quality. I find magnesium citrate crucial for kidney stones, but my husband did not notice any changes. It's worth trying to see if it works for you.
7.5
Effective for kidney stones
1 people found this helpful
For urolithiasis, magnesium citrate was prescribed by my urologist to dissolve oxalates in my kidneys. I took 200 mg once a day, and because it helps with stools, it’s a suitable option. If my review helped you, please let me know.
9
High bioavailability confirmed
Magnesium citrate is an affordable and highly bioavailable form of magnesium. Clinical studies confirm that it reduces the formation of kidney stones and helps to alkalinise urine.
7.5
Best magnesium form
1 people found this helpful
I’ve long sought out magnesium for my husband, who has kidney stones. This form is the best for him, and everyone knows Solgar for its excellent quality!
6
Removes stones effectively
1 people found this helpful
Magnesium citrate is suitable for those with kidney stones and helps to gradually eliminate them from the body. It also benefits those suffering from persistent constipation.
8
Dietary magnesium may reduce stones
Dietary Magnesium Intake and Kidney Stone: The National Health and Nutrition Examination Survey 2011-2018.
We wanted to understand the relationship between dietary magnesium intake and the prevalence of kidney stones. By examining data from the National Health and Nutrition Examination Survey spanning 2011 to 2018, we were able to analyze the self-reported history of kidney stones among participants.
Our findings indicated that those who consumed higher amounts of magnesium appeared to have a lower likelihood of experiencing kidney stones. Specifically, the average daily magnesium intake was lower in individuals with kidney stones, suggesting that magnesium might play a role in kidney stone formation.
In our analysis, we discovered that when grouped into different levels of magnesium intake, those in the highest intake category had significantly reduced odds of developing kidney stones compared to those in the lowest intake category. This trend suggests a protective effect of dietary magnesium against kidney stone disease.
While our results are promising, we recognize that further research is needed to determine if there is a direct causal relationship between magnesium intake and kidney stones. The evidence points towards a beneficial link, but more prospective studies will help clarify this important topic for better health outcomes.
8
Magnesium's complex role in kidney stones
Machine Learning Models Decoding the Association Between Urinary Stone Diseases and Metabolic Urinary Profiles.
We analyzed how magnesium levels in urine might influence the occurrence of kidney stones. The study involved a mix of 468 patients who had been diagnosed with various types of urinary stones and underwent a detailed 24-hour urine analysis.
Our investigation found that 24-hour urinary magnesium was positively associated with both kidney stones and stones in multiple locations. Specifically, higher levels of magnesium corresponded with increased risk for these conditions. This relationship was particularly interesting because magnesium was highly correlated with another mineral, urinary phosphorus.
On the flip side, we also identified that 24-hour urinary creatinine acted as a protective factor against kidney and ureter stones, suggesting that maintaining adequate creatinine levels could potentially help prevent these types of stones. Additionally, eGFR (estimated Glomerular Filtration Rate) was noted as a risk factor especially for ureter stones and those that appear in multiple locations.
Ultimately, our study underscores that while magnesium is linked to stone formation, there are other contributing factors at play as well. This knowledge could guide improvements in dietary or medicinal strategies aimed at preventing kidney stones, especially emphasizing the need for a balanced intake of minerals in our diets.
9
Magnesium reduces kidney stone risk
Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial.
We conducted a randomized, double-blind, placebo-controlled clinical trial to explore how magnesium treatments influence kidney stones, specifically for those with high levels of oxalate in their urine. Our study involved 90 participants with a history of calcium kidney stones, all of whom were experiencing idiopathic hyperoxaluria. They were divided into three groups receiving either magnesium oxide (MgO), magnesium citrate (MgCit), or a placebo for eight weeks, while their diets were monitored to keep nutritional intake consistent.
After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.
Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.
7
Magnesium reduces kidney stone risk
Association Between Magnesium Intake and Chronic Kidney Diseases and Kidney Stones in Adults Aged 50 years and Older: Dose-Response Analysis of a Nationally Representative Population-Based Study.
We examined the relationship between magnesium intake and the risk of kidney stones in adults aged 50 and older. By analyzing data collected from the National Health and Nutrition Examination Survey spanning over a decade, we aimed to understand whether increasing magnesium levels could help reduce the chances of developing kidney stones.
Our findings revealed that there is indeed a noteworthy link between magnesium consumption and kidney stones. Specifically, we observed that individuals who consumed higher amounts of magnesium had lower odds of experiencing kidney stones. This trend was especially significant for women, who showed a clearer inverse relationship with magnesium intake.
Interestingly, our results indicated that the protective benefits of magnesium plateau around a daily intake of 350 mg. This means that while increasing magnesium consumption can lower the risk of kidney stones, beyond this threshold, additional magnesium may not yield further benefits.
Overall, our study sheds light on the potential role of magnesium in preventing kidney stones and emphasizes the importance of maintaining a balanced diet rich in this essential mineral for individuals over 50.
8
Magnesium improves urine levels
Magnesium Supplementation Increases Urine Magnesium and Citrate in Stone Formers With Hypomagnesuria.
We aimed to find out how magnesium affects urinary levels of magnesium and citrate in people who form kidney stones and have low magnesium in their urine. By examining medical records, we compared two approaches: one group increased their magnesium through foods, while the other group received magnesium supplements.
We focused on adult patients whose urine magnesium levels were less than 70 mg a day. Following our recommendations, we observed significant changes after both dietary increases and supplementation. Those who took magnesium supplements showed a more pronounced improvement—about 88% were able to raise their urine magnesium to at least 70 mg a day, compared to just 58% in the dietary group.
Interestingly, only the supplement group showed a noticeable increase in urine citrate levels, which is also crucial in the prevention of kidney stones. Overall, both dietary and supplemental magnesium effectively improved magnesium levels, but supplementation had greater success in achieving desirable levels.
References
Zhang J, Luo H, Wu H, Qian Y, Tang Z, et al. The association between domestic water hardness and kidney stone disease: a prospective cohort study from the UK Biobank. Int J Surg. 2025;111:1957. doi:10.1097/JS9.0000000000002198
Ma L, Qiao Y, Wang R, Chen H, Liu G, et al. Machine Learning Models Decoding the Association Between Urinary Stone Diseases and Metabolic Urinary Profiles. Metabolites. 2024;14. doi:10.3390/metabo14120674
Zhao H, Wang Y, Guan L, Sun Y. Association Between Magnesium Intake and Chronic Kidney Diseases and Kidney Stones in Adults Aged 50 years and Older: Dose-Response Analysis of a Nationally Representative Population-Based Study. J Ren Nutr. 2024. doi:10.1053/j.jrn.2024.11.004
Vittori M, Bove P, Signoretti M, Cipriani C, Gasparoli C, et al. Oral supplementation with probiotics, potassium citrate, and magnesium in reducing crystalluria in stone formers: A phase II study. Urologia. 2024;91:681. doi:10.1177/03915603241272146
Taheri M, Jalali S, Borumandnia N, Tavasoli S, Basiri A, et al. Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial. Magnes Res. 2024;37:12. doi:10.1684/mrh.2024.0524
Penniston KL, Coughlin MM, Jhagroo RA. Magnesium Supplementation Increases Urine Magnesium and Citrate in Stone Formers With Hypomagnesuria. J Ren Nutr. 2024. doi:10.1053/j.jrn.2024.06.002
Li Q, Krieger NS, Yang L, Asplin J, Bushinsky DA. Magnesium Decreases Urine Supersaturation but Not Calcium Oxalate Stone Formation in Genetic Hypercalciuric Stone-Forming Rats. Nephron. 2024;148:480. doi:10.1159/000534495
Shringi S, Raker CA, Tang J. Dietary Magnesium Intake and Kidney Stone: The National Health and Nutrition Examination Survey 2011-2018. R I Med J (2013). 2023;106:20.
Rodriguez-Hesles CA, Alkhatatbeh H, Alonso Bartolomé MB, Valladares Ferreiro CA, Ayllón Blanco HR, et al. Urine alkalinization for dissolution of uric acid stones and treatment of other urological diseases with a treatment combining potassium magnesium citrate and theobromine. Arch Ital Urol Androl. 2025;97:13824. doi:10.4081/aiua.2025.13824